![]() In general, it is recommended to stop administering IVLE if the serum/plasma is grossly lipaemic. When considering CRIs, bear in mind that there is no evidence for efficacy of this approach. However, if using as a continuous-rate infusion (CRI) for more than 1 hour, then attention should be paid to the level of the sterility of the catheter that is used. You do not need a dedicated IV line, as it is delivered over a short period of time. The IV catheter should be checked for patency before starting the infusion, and the catheter should be flushed well after use. It is ideal to consider each bottle to be single-use only. Once the bottle is punctured, it should be discarded within 24 hours due to risk of bacterial growth in the solution. ![]() It is traditionally used for providing a fat source in parenteral nutrition formulations but in recent times, certainly in our hospital, it is more frequently used as poison antidote therapy. It is usually provided as a sterile 20% solution of soybean oil, egg phospholipids and glycerine suspended in water. Intravenous lipid emulsion therapy involves injection of a fairly large dose of lipid emulsion over a short period of time in order to counteract the effects of particular toxins. Although there is some evidence for its efficacy in specific toxicoses, its unbridled use in clinical toxicology is still controversial. There has been much interest in the use of intravenous lipid emulsion (IVLE) therapy for many different types of small animal toxicoses in the last 10 years.
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